Young Sheldon initially centers on Sheldon Cooper at the age of nine, going to high school and living with his family in the fictional town of Medford, East Texas, Sheldon's mother Mary, his father and the head football coach at Medford High, George Sr., his twin sister Missy, his older brother George Jr., and his grandmother Constance "Connie" Tucker, also known as "MeeMaw". ![]() Celebrities such as Stephen Hawking appear in cameo roles as themselves. Included among them are parents of the main characters, their dates and their coworkers. The series also features numerous supporting characters, each of whom plays a prominent role in a story arc. Over time, several supporting characters have been introduced and promoted to starring roles, including coworker and romantic partner of Leonard (and later Howard) Leslie Winkle, Sheldon's wife Amy Farrah Fowler, Howard's wife Bernadette Rostenkowski-Wolowitz, comic book store proprietor and friend of the other characters Stuart Bloom, and Emily Sweeney (though the Emily character was introduced as a girlfriend for Raj and when those characters broke up Emily no longer appeared). ![]() The Big Bang Theory cast at Comic-Con 2009, from left: Kunal Nayyar, Simon Helberg, Kaley Cuoco, Jim Parsons, and Johnny Galecki
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